Clinical manifestations, diagnosis, and natural history of alpha-1 antitrypsin deficiency
نویسندگان
چکیده
INTRODUCTION — Alpha-1 antitrypsin (AAT) deficiency is a clinically underrecognized inherited disorder affecting the lung, liver, and rarely skin. The characteristics of the pulmonary manifestations of this disorder will be reviewed here [1-4]. Extrapulmonary disease and therapy are discussed separately. (See "Extrapulmonary manifestations of alpha-1 antitrypsin deficiency" and "Treatment of alpha-1 antitrypsin deficiency".)
منابع مشابه
Alpha 1-antitrypsin deficiency. 3: Clinical manifestations and natural history.
A review of the clinical manifestations of alpha(1)-antitrypsin (AAT) deficiency, including lung disease and liver disease, and risk factors affecting the rate of decline in lung function in AAT deficient patients.
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